Aciclovir Pregnancy Use

Classified as a Category B Drug, the CDC and others accept declared that during astringent alternate or aboriginal episodes of animal herpes, aciclovir may be used. For astringent HSV infections (especially broadcast HSV), IV aciclovir may aswell be used. Studies in mice, rabbits and rats (with doses added than 10 times the agnate of that used in humans) accustomed during organogenesis accept bootless to authenticate bearing defects. Studies in rats in which they were accustomed the agnate to 63 times the accepted steady-state bodies concentrations of the drug on day 10 of evolution showed arch and appendage anomalies.

Aciclovir is recommended by the CDC for analysis of varicella during pregnancy, abnormally during the additional and third trimesters.

Aciclovir is excreted in the breast milk, accordingly it is recommended that attention should be used in breast-feeding women. It has been apparent in bound analysis studies that the nursing baby is apparent to about 0.3 mg/kg/day afterward articulate administering of aciclovir to the mother. If nursing mothers accept herpetic lesions abreast or on the breast, breast-feeding should be avoided.