Atorvastatin Pharmacodynamics

Atorvastatin, a selective, aggressive HMG-CoA reductase inhibitor, is used to lower serum absolute and LDL cholesterol, apoB, and triglyceride levels while accretion HDL cholesterol. Top LDL-C, low HDL-C and top TG concentrations in the claret are associated with added accident of atherosclerosis and cardiovascular disease.

The absolute cholesterol to HDL-C arrangement is a able augur of coronary avenue ache and top ratios are associated with college accident of disease. Added levels of HDL-C are associated with lower cardiovascular risk. By abbreviating LDL-C and TG and accretion HDL-C, atorvastatin reduces the accident of cardiovascular anguish and mortality. Atorvastatin has a different structure, continued half-life, and hepatic selectivity, answer its greater LDL-lowering authority compared to added HMG-CoA reductase inhibitors.