Isopropylamine, also called 2-aminopropane, 2-propanamine,
monoisopropylamine, and MIPA, is an organic compound, an amine. It is a base,
as typical for amines. It is a hygroscopic colorless liquid with ammonia-like
odor. Its melting point is −95.2 °C and its boiling point is 32.4 °C. It is miscible
with water. It is extremely flammable, with flash point at −37 °C.
pKa of protonated form is 10.63
Isopropylamine can be obtained by aminating isopropyl alcohol
with ammonia in presence of a nickel/copper or similar catalyst:
(CH3)2CHOH + NH3 → (CH3)2CHNH2 + H2O
The main uses of isopropylamine are in glyphosate herbicide
formulations, a key component of atrazine (another herbicide), a regulating
agent for plastics, intermediate in organic synthesis of coating materials,
plastics, pesticides, rubber chemicals, pharmaceuticals and others, and as an
additive in the petroleum industry.
Together with isopropyl alcohol it is used in some binary
chemical weapons (e.g. M687), as a mixture called OPA which in turn mixed with
methylphosphonyl difluoride (known to the military produces sarin gas.
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