CAS
No.: 229305-39-9
Molecular
Formula: C16H19N3O5
Molecular
Weight: 333.34
Purity:
98%
Golotimod
is an orally bioavailable constructed peptide absolute the amino acids
D-glutamine and L-tryptophan affiliated by a gamma-glutamyl bond with abeyant
immunostimulating, antimicrobial and antineoplastic activities. Although the
exact apparatus of activity is unknown, golotimod appears to arrest the
announcement of STAT-3, abandoning immunosuppression and aesthetic an
anti-tumor allowed response. This abettor may actuate the assembly of
T-lymphocytes, in accurate the abettor T (Th1) cells, actuate macrophages, and
access levels of interleukin 2 and interferon gamma. STAT-3, a archetype agency
upregulated in abounding blight corpuscle types, is complex in bump corpuscle
advance and adaptation and immunosuppression.
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